Recombinant Human MCP-2
Recombinant Human MCP-2
Product No.: M157
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Alternate Names SCYA8, CCL8, HC14, SCYA10, Small Inducible Cytokine A8, Chemokine (C-C Motif) Ligand 8, Monocyte Chemotactic, C-C Motif Chemokine 8 Product Type Recombinant Protein Expression Host E. coli Cells Species Human |
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BackgroundMonocyte chemotactic protein-2 (MCP-2) is a non-glycosylated polypeptide that is a member of the C-C chemokine subfamily and it specifically attracts monocytes, lymphocytes, basophils and eosinophils. It also plays a role in neoplasia and inflammatory host responses. MCP-2 can bind heparin.1 Protein DetailsPurity >97% by SDS-PAGE and analyzed by silver stain. Endotoxin Level <0.01 EU/µg as determined by the LAL method Biological Activity The biological activity of Human MCP-2 was determined by by its ability to chemoattract mouse BaF/3 cells transfected with hCCR5 and its ability to chemoattract THP-1 cells. The expected ED<sub>50</sub> for these effects are typically 0.03 - 0.12 μg/ml and 0.03 - 0.1 μg/ml, respectively. Protein Accession No. Amino Acid Sequence qpdsvsi pitccfnvin rkipiqrles ytritniqcp keavifktkr gkevcadpke rwvrdsmkhl dqifqnlkp
N-terminal Sequence Analysis Gln24 State of Matter Lyophilized Predicted Molecular Mass The predicted molecular weight of Recombinant Human MCP-2 is Mr 9 kDa. Predicted Molecular Mass 9 Formulation This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives. Storage and Stability This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. Country of Origin USA Shipping Next Day Ambient NCBI Gene Bank References & Citations1. Van Damme, J. et al. (1998) J. Immunol. 160: 4034 Certificate of AnalysisIMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein. |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
