Normal Bovine IgG Ultra, Whole Molecule
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Antibody DetailsProduct DetailsHost Species Bovine Product Concentration 5.0 - 15 mg/ml Formulation This product has been aseptically packaged and formulated in phosphate buffered saline (PBS) pH 7.1-7.5 with no carrier proteins or preservatives. Product may be provided with carrier proteins or preservatives by request Storage and Handling Store at 2-8° C under sterile conditions Expiration Date One year after date of receipt Country of Origin USA Shipping Next Day 2-8°C RRIDAB_2893535 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionBackground Normal Bovine IgG Ultra, Whole Molecule was purified using protein G chromatography fromnormal serum. IgG is produced and secreted by plasma B cells, and constitutes the majority of serumimmunoglobulins. The whole IgG molecule contains both the F(c) region, recognized by high-affinity Fcreceptor proteins, and the F(ab) region with the epitope-recognition site, and thus contains two antigenbinding sites. IgG antibodies mediate immunological responses to allergy and pathogenic infections bybinding to viruses, bacteria, or fungi and facilitating their destruction by activation of the complimentcascade, immobilizing them via agglutination, or opsinization for phagocytosis. This product contains asufficient quantity of endogenous IgG to block nonspecific binding sites on fixed samples and assaysubstrates. While most commonly used in flow cytometry this product is useful in other applicationssuch as ELISA, IHC, ICC, Blocking and as a control. References & Citations |
