Anti-Angiotensin Converting Enzyme Antibody (19501)
Anti-Angiotensin Converting Enzyme Antibody (19501)
Product No.: 19501
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Clone 3.1.1 Target Angiotensin Converting Enzyme Formats AvailableView All Product Type Monoclonal Alternate Names ACE, EC 3.2.1.-, EC 3.4.15.1, Dipeptidyl carboxypeptidase I, Kininase II, CD antigen CD143 [Cleaved into: Angiotensin-converting enzyme, soluble form] Isotype Mouse IgM Applications ELISA , FACS , IHC |
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Antibody DetailsProduct DetailsReactive Species Human, Mouse, Bovine Host Species Mouse Immunogen ACE purified from rat lung. Product Concentration Lot Specific Formulation This monoclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.2 - 7.4 with no carrier protein or preservatives added. State of Matter Liquid Product Preparation Antibodies are purified by a multi-step process including the use of PEG purification chromatography. Storage and Handling Upon initial thawing, appropriately aliquot and store at -80°C. For long-term storage, keep at -80°C. Avoid repeated freeze-thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco This antibody may be used in ELISA,
Immunohistochemistry, and flow cytometry for detection of ACE or ACE-positive cells. Other applications are under investigation. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity This antibody reacts specifically with human, bovine, and murine ACE and with ACE-positive endothelial cells. Function Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. NCBI Gene Bank ID UniProt.org Research Area Enzymes References & CitationsAuerbach, R. et al. (1982) Proc Natl Acad Sci USA 79: 7891. Technical Protocols FACS  Certificate of Analysis |
Formats Available
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Prod No. | Description |
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34043 | |
19501 |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
