Anti-Corticotropin Releasing Factor Antibody (56102)
Anti-Corticotropin Releasing Factor Antibody (56102)
Product No.: 56102
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Clone 5D5 Target Corticotropin Releasing Factor Formats AvailableView All Product Type Monoclonal Alternate Names Corticotropin-releasing factor, CRF, Corticotropin-releasing hormone Isotype Mouse IgG1 Applications ELISA |
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Antibody DetailsProduct DetailsReactive Species Human ⋅ Rat Host Species Mouse Immunogen Purified human/rat corticotropin-releasing factor (CRF, Sigma). Product Concentration Lot Specific Formulation PBS, pH 7.4. State of Matter Liquid Product Preparation Three sequential
precipitations with 40% ammonium
sulfate. Purified antibodies yield 1 band
in native SDS-PAGE. Storage and Handling These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco These antibodies may be used in immunoassays to detect and quantitate CRF. Other applications are under investigation. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity These antibodies react specifically with
CRF. There is no cross-reactivity with
bovine serum albumin, insulin,
ovalbumin, or epidermal growth factor.
These two antibodies recognize
different epitopes on CRF. Dissociation
constants = 10-9 M for 56101and 1.5 x10-8 M for 56102. Function Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity). {UniProtKB:P06296, UniProtKB:Q8CIT0}. NCBI Gene Bank ID UniProt.org Research Area Neuroscience References & CitationsKravchenko and Furalev. 1994. Hybridoma 13: 59-64 Furalev et al. 1994. Biochem Biophys Res Com 204: 823-834. Technical Protocols Certificate of Analysis |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
