Anti-β-Defensin-3 Antibody (18713)
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Antibody DetailsProduct DetailsReactivity Species Human Host Species Rabbit Immunogen Full-length human beta- defensin 3. Product Concentration Lot Specific Formulation PBS, pH 7.4 with 0.02% sodium azide State of Matter Liquid Product Preparation Purified by immunoaffinity chromatography Storage and Handling This antibody is stable for at least one (1) year at -20°C to -70°C. Store antibody in appropriate aliquots to avoid multiple freeze-thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco Immunoblotting: use at 1:500-1:1,000 dilution. In immunoblots, a band of approximately 5 kD is detected. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Rabbit Polyclonal Antibody specific to beta-Defensin-3 Background Beta-defensin-3, a nonhemolytic
antimicrobial peptide originally isolated
from human lesional psoriatic scales
and cloned from human keratinocytes.
Beta-defensin-3 appears to play a role
in natural epithelial defense against
infections by a broad spectrum of
pathogenic microorganisms. Antigen DetailsFunction Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. {PubMed:11085990}. NCBI Gene Bank ID UniProt.org Research Area Infectious Disease References & CitationsTechnical Protocols |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
