Anti-Dengue, NS1 (DENV-7846)
Anti-Dengue, NS1 (DENV-7846)
Product No.: D220
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Clone DENV-7846 Target NS1 Formats AvailableView All Product Type Hybridoma Monoclonal Antibody Isotype Mouse IgG1 Applications ELISA , IF |
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Antibody DetailsProduct DetailsReactivity Species Dengue Virus Host Species Mouse Product Concentration ≥1.0 mg/ml Purity ≥90% Formulation Formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration. State of Matter Liquid Product Preparation This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations. Storage and Handling This purified antibody is stable when stored at 2-8°C. Do not freeze. Regulatory Status Research Use Only Country of Origin USA Shipping 2-8°C Wet Ice Applications and Recommended Usage? Quality Tested by Leinco ELISA: 1:20-1:200, IF: 1:10-1:50 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Anti-Dengue virus (Clone DENV-7846) is specific for NS1 of all four serotypes of Dengue virus. Matched Pair Best pair (capture/detection), DENV-7846/DENV-1679 Background Dengue virus (DENV) is the most common insect-transmitted virus to target humans, with an estimated 390 million infections annually1. DENVs are members of the Flaviviridae family (single-stranded, positive-sense RNA viruses) and can be divided into four closely related but antigenically distinct serotypes2. Encoded in the genome is NS1 (Non-Structural Protein 1) which plays a critical role in the viral life cycle and interacts with the host immune system. NS1 is present in the serum of infected individuals and can be detected early during acute infection, making it a valuable diagnostic marker for dengue fever. Antigen DetailsResearch Area Category A Pathogens . Infectious Disease . Matched Pair . Viral . IVD Raw Material References & Citations1. Smith SA, de Alwis AR, Kose N, et al. mBio. 4(6):e00873-13. 2013.
2. Lecouturier V, Berry C, Saulnier A, et al. Vaccine. 37(32):4601-4609. 2019. Technical Protocols IF |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
