Anti-Factor V Heavy Chain Antibody (19702)
Anti-Factor V Heavy Chain Antibody (19702)
Product No.: 19702
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Clone B10 Target Factor V Heavy Chain Formats AvailableView All Product Type Monoclonal Alternate Names Activated protein C cofactor, Proaccelerin, labile factor [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain] Isotype Mouse IgG1 Applications ELISA , IHC , Autorad |
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Immunogen Purified human Factor V. Product Concentration Lot Specific Formulation PBS, pH 7.4. State of Matter Liquid Product Preparation Purified by Protein G affinity chromatography Storage and Handling These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco This antibody may be used in ELISA,
Immunohistochemistry, and autoradiography. Other applications are under investigation. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Mouse Monoclonal Antibody reacts with the activation C peptide (mw ~150,000) in the
heavy chain of thrombin-cleaved
human Factor V. KD = 1.15 x 10-10
mol/L. Background Coagulation cofactor V (Factor V) is a high molecular weight glycoprotein that performs several critical functions in regulating hemostasis. In its thrombin-activated form (FVa) it interacts with Factor Xa and Ca+2 to form the prothrombinase complex. This complex catalyzes the formation of thrombin from prothrombin at rates substantially higher than Factor Xa alone. Function Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin. NCBI Gene Bank ID UniProt.org Research Area Coagulation factors References & CitationsGewirtz, AM et al. (1986) Blood 67: 1639. Technical Protocols  Autorad Certificate of Analysis |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
