Anti-Group A Streptococcal Polysaccharide – Biotin

Anti-Group A Streptococcal Polysaccharide – Biotin

Product No.: S247

- -
- -
Clone
2S1.3
Target
Group A Streptococcal Polysaccharide
Formats AvailableView All
Product Type
Recombinant Monoclonal Antibody
Alternate Names
Group A Streptococcal Polysaccharide
Isotype
Mouse IgG1 κ

- -
- -
Select Product Size
- -
- -

Antibody Details

Product Details

Reactive Species
Bacteria
Host Species
Mouse
Immunogen
Group A Streptococcal Polysaccharide
Product Concentration
0.5 mg/ml
Formulation
This Biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
State of Matter
Liquid
Storage and Handling
This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
Regulatory Status
Research Use Only
Country of Origin
USA
Shipping
2 – 8° C Wet Ice
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Description

Specificity
Clone 2S1.3 specifically targets the polysaccharide antigens present on the surface of Group A Streptococcus (GAS) bacteria.
Background
Streptococcus bacteria are a type of gram-positive bacteria that are classified into different groups based on their serological characteristics. Among them, Group A and Group B Streptococcus are particularly important for medical purposes, as they can cause serious infections1, 2. Group A Streptococcus is a genus of gram-positive bacteria that can cause both pathogenic and commensal infections. These bacteria are particularly significant in medicine because they can lead to severe infections, including pharyngitis, scarlet fever, and rheumatic fever3.

When it comes to diagnosing streptococcal infections, monoclonal antibodies such as Clone 2S1.3 play an important role. This antibody is used to detect specific anti-polysaccharide antibodies in patients with streptococcal infections. The clone has been studied using enzyme immunoassay (EIA) and passive hemagglutination reaction (PHR) to detect specific anti-polysaccharide antibodies and has shown a broad spectrum of antibody titers4. In the case of streptococcal infections, monoclonal antibodies such as Clone 2S1.3 can help doctors diagnose the infection more accurately and provide more targeted treatment to patients.

Antigen Distribution
Group A Streptococcus bacteria commonly colonize mucosal surfaces such as the mouth, nares, and pharynx in humans and animals like horses, pigs, and cows. They can also be found on the skin, heart, or muscle tissue under certain conditions.
Research Area
Immunology
.
Infectious Disease
.
Nosocomial
.
IVD Raw Material

References & Citations

1. Riesen WF, Skvaril F, Braun DG. Scand J Immunol. 1976;5(4):383-390.
2. Widdowson JP, Maxted WR, Pinney AM. J Med Microbiol. 1976;9(1):73-88.
3. Steer AC, Danchin MH, Carapetis JR. J Paediatr Child Health. 2007;43(4):203-213.
4. Burova LA, Gladilina MM, Semykina LV, Murashov SV. Vestn Akad Med Nauk SSSR. 1989;(11):12-17.
5. Root-Bernstein R. Front Pediatr. 2014;2:85.
6. Barrett DJ, Triggiani M, Ayoub EM. J Clin Microbiol. 1983;18(3):622-627.
7. Ruch FE, Smith L. J Clin Microbiol. 1982;16(1):145-152.
8. Gupta R, Rattan A, Prakash K, Talwar GP, Gupta S. The Indian journal of medical research. Published online 1993. Accessed February 1, 2024.

Formats Available

- -
- -
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.