Anti-Herpes Simplex Virus, gD (HSV-0846)
Anti-Herpes Simplex Virus, gD (HSV-0846)
Product No.: H280
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Clone HSV-0846 Target Glycoprotein D, gD Formats AvailableView All Product Type Hybridoma Monoclonal Antibody Alternate Names HSV, HSV-1, HSV-2 Isotype Mouse IgG1 Applications ELISA , IF , Lateral Flow |
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Antibody DetailsProduct DetailsReactivity Species Herpes Simplex Virus 1 and 2 Host Species Mouse Product Concentration ≥1.0 mg/ml Purity ≥90% Formulation Formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration. State of Matter Liquid Product Preparation This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations. Storage and Handling This purified antibody is stable when stored at 2-8°C. Do not freeze. Regulatory Status Research Use Only Country of Origin USA Shipping 2-8°C Wet Ice Applications and Recommended Usage? Quality Tested by Leinco ELISA: 1:20-1:200, Lateral Flow, IF: 1:10-1:50 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Anti-HSV (Clone HSV-0846) has known reactivity for glycoprotein D (gD) of HSV 1 & 2. Matched Pair Best ELISA pair (capture/conjugate), HSV-0846/HSV-7315. Background Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are two closely related enveloped DNA viruses that are members of the Herpesviridae family of viruses. HSV is a neurotropic virus that initially infects and replicates in epithelial cells of the mucosal epithelium before it establishes lifelong latent infection within sensory neurons.
While both viruses can cause genital infection, HSV-2 is most often the cause of these infections. HSV-1 is typically spread during childhood and has a global prevalence of about 90%. Both viruses can be spread to other tissues via contact with infected skin or mucous membranes.
Glycoprotein D (gD) is the major receptor binding protein of HSV and binds to at least one of the three known entry receptors: herpesvirus entry mediator (HVEM), nectin-1, and 3-O sulfated heparan sulfate. Antigen DetailsAntigen Glycoprotein D, gD Research Area Infectious Disease . Matched Pair . Sexually Transmitted Infections . Viral . IVD Raw Material References & CitationsTechnical Protocols IF Lateral Flow |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
