Anti-Human APRIL (Extracellular Domain-1)

Anti-Human APRIL (Extracellular Domain-1)

Product No.: A154

[product_table name="All Top" skus="A154"]

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Target
APRIL
Product Type
Polyclonal Antibody
Alternate Names
A Proliferating-Inducing Ligand, CD256, TNFSF13, TALL2, TRDL1
Applications
WB

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Rabbit
Immunogen
PN:A185
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Description

Specificity
Rabbit Anti-Human APRIL recognizes an epitope in the extracellular domain of Human APRIL. This polyclonal antibody was purified using affinity chromatography.
Background
A proliferation-inducing ligand (APRIL) is a TNF-like cytokine that stimulates tumor cell growth.1 It is of low abundance in normal tissues.2 APRIL acts as a proliferative factor in megakaryocytopoiesis, a developmental hematopoietic process responsible for progenitor cell differentiation to megakaryoblasts and megakaryocytes, leading to platelet formation.3 APRIL may be implicated in the regulation of tumor cell growth.2
PubMed
NCBI Gene Bank ID

References & Citations

1. Sarah G. Hymowitz et al. (2004) J Mol Biol. 343: 283 2. (1998) Jürg Tschopp 3. Ruggero De Maria et al. (2004) Blood 104: 3169
General Western Blot Protocol

Certificate of Analysis

Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.