Anti-Human CD14 - FITC - Leinco Technologies

Anti-Human CD14 – FITC

Product No.: C155


Clone UCHM-1 Target CD14 Formats AvailableView All Product Type Monoclonal Antibody Alternate Names P35, LPS receptor Isotype IgG2a Applications FC


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Data


Antibody Details Product Details Reactive Species Human Host Species Mouse Product Concentration 0.2 mg/ml Formulation This Fluorescein (FITC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This Fluorescein conjugate is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day Ambient Excitation Laser Blue Laser (490 nm) RRIDAB_2828620 Applications and Recommended Usage? Quality Tested by Leinco FC The suggested concentration for this UCHM-1 antibody for staining cells in flow cytometry is ≤ 1.0 μg per 10⁶ cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. Description Description Specificity Clone UCHM-1 recognizes an epitope on human CD14. Background CD14 is a 53-55 kD GPI-anchored single chain glycoprotein that plays a role in the clearance of gram-negative pathogens by interacting with other proteins, including TLR-4 and MD-2, to mediate the innate immune response to bacterial lipopolysaccharide (LPS). As a high-affinity receptor for LPS, it is involved in the upregulation of adhesion molecules and cytokine expression in monocytes and neutrophils. Antigen Distribution CD14 is expressed on monocytes, macrophages, dendritic cells, and granulocytes. Ligand/Receptor LPS PubMed CD14 NCBI Gene Bank ID 929 UniProt.org Information on Uniprot.org Research Area Cell Biology . Immunology . Neuroinflammation . Neuroscience References & Citations 1. Ulrich Costabel et al. (1995) CHEST 108: 1614 2. Ulevitch RJ et al. (1993) Immunobiology 187: 227 3. Schumann RR et al. (1994) Medical Microbiol Immunol. 183: 279 4. Verhasselt V et al. (1997) J Immunol. 158: 2919 5. Kirkland TN et al. (2000) J Biol Chem. 275: 3144 View product citations for antibody PRODUCT_CODE on CiteAb Technical Protocols Certificate of Analysis Request COA

Antibody Details

Product Details

Reactive Species

Human

Host Species

Mouse

Product Concentration

0.2 mg/ml

Formulation

This Fluorescein (FITC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.

Storage and Handling

This Fluorescein conjugate is stable when stored at 2-8°C. Do not freeze.

Country of Origin

USA

Shipping

Next Day Ambient

Excitation Laser

Blue Laser (490 nm)

RRIDAB_2828620

Applications and Recommended Usage?
Quality Tested by Leinco

FC The suggested concentration for this UCHM-1 antibody for staining cells in flow cytometry is ≤ 1.0 μg per 10⁶ cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application.

Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity

Clone UCHM-1 recognizes an epitope on human CD14.

Background

CD14 is a 53-55 kD GPI-anchored single chain glycoprotein that plays a role in the clearance of gram-negative pathogens by interacting with other proteins, including TLR-4 and MD-2, to mediate the innate immune response to bacterial lipopolysaccharide (LPS). As a high-affinity receptor for LPS, it is involved in the upregulation of adhesion molecules and cytokine expression in monocytes and neutrophils.

Antigen Distribution

CD14 is expressed on monocytes, macrophages, dendritic cells, and granulocytes.

Ligand/Receptor

LPS

PubMed

CD14

NCBI Gene Bank ID

929

UniProt.org

Information on Uniprot.org

Research Area

Cell Biology

Immunology

Neuroinflammation

Neuroscience

References & Citations

1. Ulrich Costabel et al. (1995) CHEST 108: 1614 2. Ulevitch RJ et al. (1993) Immunobiology 187: 227 3. Schumann RR et al. (1994) Medical Microbiol Immunol. 183: 279 4. Verhasselt V et al. (1997) J Immunol. 158: 2919 5. Kirkland TN et al. (2000) J Biol Chem. 275: 3144

View product citations for antibody PRODUCT_CODE on CiteAb

Certificate of Analysis

Request COA

Prod No.	Description
C1867	Anti-Human CD14 – PerCP
C1865	Anti-Human CD14 – DyLight® 755

Formats Available

Prod No.	Description
C1867	Anti-Human CD14 – PerCP
C153	Anti-Human CD14 – Purified
C154	Anti-Human CD14 – Biotin
C155	Anti-Human CD14 – FITC
C1859	Anti-Human CD14 – DyLight® 488
C1860	Anti-Human CD14 – DyLight® 550
C1861	Anti-Human CD14 – DyLight® 594
C1863	Anti-Human CD14 – DyLight® 650
C1865	Anti-Human CD14 – DyLight® 755
C156	Anti-Human CD14 – PE
C370	Anti-Human CD14 – Purified in vivo GOLD™ Functional Grade
C315	Anti-Human CD14 – APC

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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Anti-Human CD14 – FITC