Anti-Human CD2 – Biotin
Anti-Human CD2 – Biotin
Product No.: C110
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Clone G11 Target CD2 Formats AvailableView All Product Type Monoclonal Antibody Isotype IgG2a Applications FC |
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Product Concentration 0.5 mg/ml Formulation This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This biotinylated antibody is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day Ambient RRIDAB_2828322 Applications and Recommended Usage? Quality Tested by Leinco FC The suggested concentration for this G11 antibody for staining cells in flow cytometry is ≤ 1.0 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Clone G11 recognizes an epitope of human CD2. Background CD2 is a 45-59 kD type I transmembrane glycoprotein belonging to the Ig superfamily. CD2 is the receptor for LFA-3/CD58. CD2 serves as an adhesion receptor that binds to CD58; generating the activation of CD2-positive T cells and NK cells and in the regulation of their cytolytic activities. CD2 is a specific marker for T cells and NK cells. Hence, it can be used in immunohistochemistry to identify the occurrence of these cells in tissue sections. The vast majority of T cell lymphomas and leukemias express CD2 which makes it possible to distinguish these conditions from B-cell lymphomas. Antigen Distribution CD2 is present on normal peripheral blood lymphocytes, thymocytes, mature circulating T-cells and a subset of NK cells. Ligand/Receptor CD58 (LFA-3), CD48, CD59, CD15 PubMed NCBI Gene Bank ID UniProt.org Research Area Costimulatory Molecules . Immunology References & Citations1. Meuer, S.C. et al. (1984) Cell 36:897 2. Peterson, A. and Sneed, B. (1987) Nature 329:842 3. Bierer, B.E. et al. (1989) Annu. Rev Immunol. 7:579 4. Krensky, C.F. et al. (1982) Proc. Natl. Acad. Sci. USA 79:7489 5. Krensky, C.F. et al. (1983) J. Immunol. 131:611 Technical Protocols Certificate of Analysis |
Formats Available
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Prod No. | Description |
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C1839 | |
C109 | |
C111 | |
C110 | |
C1831 | |
C1833 | |
C1835 | |
C112 | |
C308 | |
C365 | |
C965 |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
