Anti-Human CD28 – Purified (PhenoCyler-Fusion (CODEX)® Ready)
Anti-Human CD28 – Purified (PhenoCyler-Fusion (CODEX)® Ready)
Product No.: C511
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Clone CD28.2 Target CD28 Formats AvailableView All Product Type Monoclonal Antibody Alternate Names MGC138290, Tp44 Isotype IgG1 κ Applications IHC FF , PhenoCycler® |
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CODEX® DetailsValidation Notes Clone CD28.2 has been validated for use on CODEX® using human tonsil Fresh Frozen (FF) tissue. Tissue Screened Tonsil Tissue Preparation FF (Fresh Frozen) Antibody and Reporter DetailsReactivity Species Human Host Species Mouse Concentration ≥ 2.0 mg/ml Formulation This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4. Storage and Handling This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Applications and Recommended Usage? Quality Tested by Leinco CODEX® This CD28 (Clone CD28.2) antibody is formulated to simplify the antibody preparation needed when performing a CODEX® barcode conjugate. The suggested concentration is 0.5 mg/ml. RRID AB_2893568 Country of Origin USA Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Clone CD28.2 recognizes an epitope on human CD28. Antigen Distribution CD28 is expressed on thymocytes, CD4+, CD8+ peripheral T cells, NK cells. Background CD28 is a 44 kD glycoprotein and a member of the Ig superfamily. In its capacity as a costimulatory receptor, CD28 produces co-stimulatory signals necessary for T cell activation and survival. CD28 is the only B7 receptor constitutively expressed on naive T cells. Without having this CD28/B7 interaction, T cells will fail to respond to their specific antigen when coming in contact with an MHC/antigen complex and thus, are said to be anergic. Antigen DetailsProtein Ligand/Receptor CD80, CD86 PubMed NCBI Gene Bank ID References & Citations1. Stern, LJ. et al. (2005) Proc Natl Acad Sci U S A.102(10):3744-9 PubMed Technical Protocols PhenoCycler® |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
