Anti-Human CD3 – APC
Anti-Human CD3 – APC
Product No.: C309
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Clone UCHT-1 Target CD3 Formats AvailableView All Product Type Monoclonal Antibody Isotype IgG1 κ Applications FC |
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Product Concentration 0.2 mg/ml Formulation This Allophycocyanin (APC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This APC conjugate is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day USA 2-8°C $30 Excitation Laser Red Laser (650 nm) RRIDAB_2829636 Applications and Recommended Usage? Quality Tested by Leinco FC The suggested concentration for this UCHT-1 antibody for staining cells in flow cytometry is ≤ .25 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Clone UCHT-1 recognizes an epitope on human CD3ε. Background CD3ε is a 20kDa subunit of the TCR complex and is a transmembrane T-cell surface glycoprotein that belongs to the Ig superfamily. It is one of five polypeptide chains that form the TCR complex by associating with the CD3δ, γ and ζ chains, in addition to the TCR α/β or γ/δ chains. CD3 is involved in TCR signaling, enumeration of immunocompetent T-lymphocytes in peripheral blood, and signal transduction during antigen recognition. Antigen Distribution CD3 is expressed on human peripheral blood lymphocytes, splenic lymphocytes, and the majority of T-CLL and T-ALL cells. Ligand/Receptor Peptide antigen bound to MHC PubMed NCBI Gene Bank ID UniProt.org Research Area Immunology References & Citations1. van Dongen, J. et al. (1988) Blood 71:603 2. Meuer, SC. et al. (1983) Nature 303:808 3. Beverly, P. et al. (1981) Eur. J. Immunol. 11:329 4. Leukocyte Typing III: Code No. 126, 208 and 471; 4th Workshop: Paper No. T3.2 Technical Protocols Certificate of Analysis |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
