Anti-Human CD61 (Integrin β3) (Clone F11) – FITC
Anti-Human CD61 (Integrin β3) (Clone F11) – FITC
Product No.: C193
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Clone F11 Target CD61 Formats AvailableView All Product Type Monoclonal Antibody Alternate Names Integrin β3 Isotype IgG1 Applications FC |
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Product Concentration 0.2 mg/ml Formulation This Fluorescein (FITC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This Fluorescein conjugate is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day Ambient Excitation Laser Blue Laser (490 nm) RRIDAB_2829010 Applications and Recommended Usage? Quality Tested by Leinco FC The suggested concentration for this F11 antibody for staining cells in flow cytometry is ≤ 1 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Mouse Anti-Human CD61 (Clone F11) recognizes Human CD61. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Anti-Human CD61 recognizes the (Mr 110 kDa) common Beta-subunit of the gp IIb/IIIa complex and the vitronectin receptor (VNR). The gp IIb (CD41) antigen and the gp IIIa (CD61) antigen form the cell adhesion complex (gp IIb/IIIa) which is the receptor on platelets for fibrinogen, von Willebrand factor, fibronectin and vitronectin. Background Anti-CD61-Fluorescein may be used to identify platelets and megakaryocytes. It may also be used in studies to characterize leukemias and in research of cell adhesion molecules. Antigen Distribution The CD61 antigen is present on virtually all resting and activated platelets. The antigen is also known to be present on endothelial cell, megakaryocytes and some leukemias of myeloid, erythroid and lymphoid origin. Ligand/Receptor Fibronectin, vitronectin, vWF PubMed NCBI Gene Bank ID UniProt.org Research Area Immunology References & Citations1. Helfrich, M. N. et al. submitted for publication
Technical Protocols Certificate of Analysis |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
