Anti-Human CDw60 (9-0-acetyl GD3) – Purified

This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.

This purified antibody is stable when stored at 2-8°C. Do not freeze.

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Mouse Anti-Human CDw60 (Clone Jones) recognizes Human CDw60. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Anti-Human CDw60 recognizes a (Mr 120 kD) carbohydrate (9-0-acetyl GD3) antigen.

The CDw60 antigen is present on gangliosides, platelets and a subset of CD4+, CD8+ peripheral T-cells, but not on B-cells, monocytes or granulocytes. CDw60 is involved in the co-stimulation of T-cells. The antigen is also detectable in some previously undescribed benign and malignant tumors. CDw60 shows different subcellular distribution patterns.

1. Leukocyte Typing V (1995) Oxford University Press 2. Blum, A. S. and Barnstable, C. J. et al. (1987) Proc. Natl. Acad. Sci. 84:8716 3. Constantine-Paton, M. et al. (1986) Nature 324:659