Anti-Human MIP-5 (Clone 88119)
Anti-Human MIP-5 (Clone 88119)
Product No.: M1274
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Clone 88119 Target MIP-5 Formats AvailableView All Product Type Monoclonal Antibody Alternate Names SCYA15, HCC-2, NCC-3, SCYL3, Lkn-1, MIP-1d, HMRP-2B, CCL15 Isotype IgG1 Applications N , WB |
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Immunogen E. coli-Derived Recombinant Human MIP-1δ/rhLKN-1 (aa 46 - 113) (Accession # Q16663) Endotoxin Level <0.1 EU/µg as determined by the LAL method Formulation This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. Storage and Handling The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months. Country of Origin USA Shipping Next Day Ambient RRIDAB_2831268 Applications and Recommended Usage? Quality Tested by Leinco Western Blotting: To detect Human MIP-5 this monoclonal antibody can be used at a concentration of 1-2 µg/ml. This monoclonal antibody should be used in conjunction with compatible second-step reagents such as PN:M114 and a chromogenic substrate such as PN:T343. The sensitivity of detection may increase up to 50 fold when a chemiluminescent substrate is used. A suitable Western blotting control is PN:M1239. Additional Applications Reported In Literature ? Neutralization: This antibody is useful for neutralization of Human MIP-1δ bioactivity. The antibody dose required to neutralize 50% (ND50) of the biological activity of Human MIP-1δ (at 10 ng/ml) is 5-20 µg/ml. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Mouse Anti-Human Macrophage Inflammatory Protein-5 (MIP-5) (Clone 88119) recognizes an epitope on Human MIP-5. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background Macrophage inflammatory protein-5 (MIP-5) is a CC chemokine is expressed at high levels in liver, intestine, and in lung leukocytes. It induces chemotaxis of monocytes, T-lymphocytes and eosinophils. MIP-5 competes with MIP-1-alpha for binding to CC-Chemokine receptor CCR1, and with MCP-3 for binding to CCR3.1 PubMed References & Citations1. Coulin, F. et al. (1997) J. Biochem. 248: 507 Technical ProtocolsN  Certificate of Analysis |
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Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
