Anti-Human NGF R

This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.

This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

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Rabbit Anti-Human Nerve Growth Factor Receptor (NGFR) recognizes Human NGFR. This polyclonal antibody was purified using affinity chromatography.

Nerve growth factor receptor (NGFR), also known as the low-affinity receptor p75NTR is a transmembrane glycoprotein without intrinsic tyrosine kinase activity, whose expression is not restricted to neural cells. NGFR is reported to act as a tumour suppressor, negatively regulating cell growth and proliferation.¹ It is also involved in several diverse functions such as apoptosis, neurite outgrowth during development, and myelination.² p75NGFR contributes to delayed neuronal death (DND) after ischemia by an apoptotic mechanism.³

1. Ashworth, A. et al. (2006) Modern Path. 19: 307
2. Carter, BD. et al. (2004) Prog. Brain Res. 146: 25
3. Itano, T. et al. (2001) Acta Med Okayama 55: 19