Anti-Human TWEAK R

This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.

This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Next Day Ambient

Rabbit Anti-Human TNF-Related Weak Inducer of Apoptosis Receptor (TWEAK R) recognizes Human TWEAK R. This polyclonal antibody was purified using affinity chromatography.

The TWEAK Receptor/FN14, also known as Tumor necrosis factor receptor superfamily member 12A precursor (TNFRSF12A) or fibroblast growth factor-inducable 14, is a secreted type I membrane protein belonging to the distinct superfamily of TNF Receptors. TWEAKR is expressed in many tissues such as the heart, placenta, kidney, pancreas, skeletal muscle and lung. TWEAK R plays a role in TWEAK-induced endothelial cell migration, proliferation, and angiogenesis.

1. Nakayama, M. et al. (2003) J. Immunol. 170:341
2. Wiley, SR. et al. (2001) Immunity 15:837
3. Feng, SL. et al. (2000) Am. J. Pathol. 156:1253
4. Desplat-Jégo, S. et al. (2005) Clin. Immunol. 117:15