Anti-Mouse CD152 (CTLA-4) – DyLight® 755
Anti-Mouse CD152 (CTLA-4) – DyLight® 755
Product No.: C1754
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Clone 9H10 Target CTLA-4 Formats AvailableView All Product Type Monoclonal Antibody Alternate Names CD152, CTLA4 Isotype IgG Applications FC |
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Antibody DetailsProduct DetailsReactive Species Mouse Host Species Syrian Hamster Immunogen Purified Recombinant Mouse CTLA-4 (>98%) Product Concentration 0.5 mg/ml Formulation This DyLight<sup>®</sup> 755 conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This DyLight® 755 conjugate is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day 2-8°C RRIDAB_2828820 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Clone 9H10 recognizes an epitope on mouse CTLA-4. Background CTLA-4 is a 33 kD member of the Ig superfamily similar to CD28 in amino acid sequence, structure, and genomic organization. CTLA-4 is a protein receptor that functions as an immune checkpoint and downregulates immune responses. It is involved in the development of protective immunity and thymocyte regulation, in addition to the induction and maintenance of immunological tolerance. CTLA-4 has therapeutic potential both as an agonist to reduce immune activity, and an antagonist to increase immune activity. Antigen Distribution CTLA-4 is expressed on activated T and B lymphocytes. Ligand/Receptor CD80 (B7-1), CD86 (B7-2) PubMed NCBI Gene Bank ID UniProt.org Research Area Immunology References & CitationsTechnical Protocols Certificate of Analysis |
Formats Available
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Prod No. | Description |
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C1756 | |
C1748 | |
C1749 | |
C1750 | |
C1752 | |
C1753 | |
C1754 | |
C1614 | |
C2841 |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
