Anti-Mouse CD3ε – PerCP
Anti-Mouse CD3ε – PerCP
Product No.: C1737
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Clone 500A2 Target CD3ε Formats AvailableView All Product Type Monoclonal Antibody Isotype IgG2a κ Applications FC |
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Antibody DetailsProduct DetailsReactive Species Mouse Host Species Syrian Hamster Immunogen Purified Recombinant Mouse CD3ε (>98%) Product Concentration 0.5 mg/ml Formulation This PerCP conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This PerCP conjugate is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day 2-8°C RRIDAB_2828801 Applications and Recommended Usage? Quality Tested by Leinco FC The suggested concentration for this 500A2 antibody for staining cells in flow cytometry is ≤ .125 μg per 106 cells in a volume of 100 μl. Titration of the reagent is recommended for optimal performance for each application. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Clone 500A2 recognizes an epitope on mouse CD3ε. Background CD3ε is a 20kDa subunit of the TCR complex and is a transmembrane T-cell surface glycoprotein that belongs to the Ig superfamily. It is one of five polypeptide chains that form the TCR complex by associating with the CD3δ, γ and ζ chains, in addition to the TCR α/β or γ/δ chains. CD3 is involved in TCR signaling, enumeration of immunocompetent T-lymphocytes in peripheral blood, and signal transduction during antigen recognition. Antigen Distribution CD3ε is primarily expressed on mature T cells and NK-T cells and at different levels on differentiation-dependent thymocytes. Ligand/Receptor Peptide antigen/MHC-complex. PubMed NCBI Gene Bank ID UniProt.org Research Area Cell Biology . Immunology . Signal Transduction References & Citations1. Havran, WM. et al. (1987) Nature 330:170 2. Allison, JW. et al. (1988) The T-Cell Receptor 33 Technical Protocols Certificate of Analysis |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
