Anti-Mouse CXCL7 (Clone 159742)
Anti-Mouse CXCL7 (Clone 159742)
Product No.: C1380
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Clone 159742 Target CXCL7 Formats AvailableView All Product Type Monoclonal Antibody Alternate Names PPBP, PBP, B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, LA-PF4, LDGF, MDGF, Neutrophil Activating Peptide 2 (NAP-2), SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1, Thymus Chemokine-1, Chemokine (C-X-C Motif) Ligand 7 Isotype IgG2b Applications N , WB |
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Antibody DetailsProduct DetailsReactive Species Mouse Host Species Rat Immunogen Purified Recombinant Mouse CXCL7 (>98%) Formulation This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. Storage and Handling The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months. Country of Origin USA Shipping Next Day Ambient RRIDAB_2828436 Applications and Recommended Usage? Quality Tested by Leinco Western Blotting: To detect Mouse CXCL7 this monoclonal antibody can be used at a concentration of 1-2 µg/ml. This monoclonal antibody should be used in conjunction with compatible second-step reagents such as PN:R377 and a chromogenic substrate such as PN:T343. The detection limit for Mouse CXCL7 is 25 ng/lane under either reducing or non-reducing conditions. The sensitivity of detection may increase up to 50 fold when a chemiluminescent substrate is used. A suitable Western blotting control is PN:T380. Additional Applications Reported In Literature ? Neutralization: This antibody is useful for neutralization of Mouse CXCL7 bioactivity. The antibody dose required to neutralize 50% (ND50) of the biological activity of Mouse CXCL7 (at 40 ng/ml) is 2-8 µg/ml. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Rat Anti-Mouse CXCL7 (Clone 159742) recognizes an epitope on Mouse CXCL7. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. In direct ELISAs, this antibody shows no cross-reactivity with other chemokines tested. Background CXC chemokine ligand 7 is a small cytokine belonging to the CXC chemokine family. It is a protein that is released in large amounts from platelets following their activation.1 It stimulates various processes including mitogenesis, synthesis of extracellular matrix, glucose metabolism and synthesis of plasminogen activator.2,3 PubMed Research Area Chemokine References & Citations1. Poncz, M. et al. (1991) J Biol Chem. 266: 5785 2. Walz, D. et al. (1983) Proc Natl Acad Sci USA 80: 765 3. Carter-Su, C. et al. (1985) Biochemistry 24: 1762 Technical ProtocolsN  Certificate of Analysis |
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Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
