Anti-Mouse/Human TGF-β Antibody – Purified in vivo GOLD™ Functional Grade
Anti-Mouse/Human TGF-β Antibody – Purified in vivo GOLD™ Functional Grade
Product No.: T699
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Clone 1D11.16.8 Target TGF-β Formats AvailableView All Product Type Monoclonal Antibody Alternate Names TGFB, DPD1, TGFB1, Differentiation Inhibiting Factor, Cartilage-Inducing Factor, Latency Associated Isotype Mouse IgG1 Applications IHC , in vivo , N , WB |
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Antibody DetailsProduct DetailsReactive Species Bovine ⋅ Hamster ⋅ Human ⋅ Mouse ⋅ Rat Host Species Mouse Recommended Isotype Controls Recommended Isotype Controls Recommended Dilution Buffer Immunogen Bovine TGFβ isoform 2 Product Concentration ≥ 5.0 mg/ml Endotoxin Level < 1.0 EU/mg as determined by the LAL method Purity ≥95% monomer by analytical SEC ⋅ >95% by SDS Page Formulation This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration. Product Preparation Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. Storage and Handling Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day 2-8°C RRIDAB_2737573 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity This Mouse Anti-Human/Mouse TGF-β clone Clone 1D11.16.8 recognizes an epitope on Human/Mouse TGF-β1,2,3. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Ligand/Receptor Heterodimeric receptor consisting of type I (TbRI) and type II (TbRII). Research Area Apoptosis . Cell Biology . Cell Death . Immunology . Neuroinflammation . Neuroscience . Signal Transduction . Tumor Suppressors References & Citations1. Guven, M. et al. (2007) Growth Factors 25: 101 2. Schneider, J. et al. (2009) J Investing Med. 57(5):655-61 3. Yu, C. et al. (2009) Biochem Biophys Res Commun. 406(2):204-210 Technical ProtocolsCertificate of Analysis |
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Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.