Anti-Mouse IFN-γ (Clone H22) – DyLight® 594
Anti-Mouse IFN-γ (Clone H22) – DyLight® 594
Product No.: I-980
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Clone H22 Target IFN-γ Formats AvailableView All Product Type Monoclonal Antibody Alternate Names Immune Interferon, Type II Interferon, T Cell Interferon, MAF, IFNG, IFG, IFI Isotype IgG Applications IF |
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Antibody DetailsProduct DetailsReactive Species Mouse Host Species Armenian Hamster Immunogen Purified Recombinant Mouse IFN-γ (>98%) Product Concentration 0.2 mg/ml Formulation This DyLight® 594 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This DyLight® 594 conjugate is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day 2-8°C Excitation Laser Red Laser (590 nm) RRIDAB_2831056 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Armenian Hamster Anti-Mouse Interferon Gamma (IFN-γ) (Clone H22) recognizes an epitope on Mouse IFN-γ. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.1 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.2 IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.3 PubMed NCBI Gene Bank ID UniProt.org Research Area Immunology References & Citations1. Goeddel DV et al. (1982) Nature 298: 859
2. Wilson CB et al. (2007) Adv. Immunol. 96: 41
3. Hume DA et al. (2004) J Leukoc Biol. 75: 163 |
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Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.