Anti-Mouse IGFBP-6 (Clone 122316)

Product No.: I-706


Clone 122316 Target IGFBP-6 Formats AvailableView All Product Type Monoclonal Antibody Alternate Names IBP6, Insulin-Like Growth Factor Binding Protein 6 Isotype IgG2b Applications WB


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Antibody Details Product Details Reactive Species Mouse Host Species Rat Immunogen NS0-Derived Recombinant Mouse IGFBP-6 Endotoxin Level <0.1 EU/µg as determined by the LAL method Formulation This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. Storage and Handling The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months. Country of Origin USA Shipping Next Day Ambient RRIDAB_2830827 Applications and Recommended Usage? Quality Tested by Leinco Western Blotting: To detect Mouse IGFBP-6 this monoclonal antibody can be used at a concentration of 1-2 µg/ml. This monoclonal antibody should be used in conjunction with compatible second-step reagents such as PN:R377 and a chromogenic substrate such as PN:T343. The detection limit for Mouse IGFBP-6 is 6 ng/lane under either reducing or non-reducing conditions. The sensitivity of detection may increase up to 50 fold when a chemiluminescent substrate is used. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. Description Description Specificity Rat Anti-Mouse Insulin-Like Growth Factor Binding Protein 6 (IGFBP-6) (Clone 122316) recognizes an epitope on Mouse IGFBP-6. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background Insulin-like growth factor binding protein 6, also known as IGFBP6 an extracellular protein with preferential affinity for insulin-like growth factor (IGF) II.¹ IGFBP6 plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase and may provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa. PubMed IGFBP-6 NCBI Gene Bank ID 16012 UniProt.org Information on Uniprot.org References & Citations 1. Luthman, H. et al. (1999) Mamm Genome. 10: 376 View product citations for antibody PRODUCT_CODE on CiteAb Technical Protocols Certificate of Analysis Request COA

Antibody Details

Product Details

Reactive Species

Mouse

Host Species

Rat

Immunogen

NS0-Derived Recombinant Mouse IGFBP-6

Endotoxin Level

<0.1 EU/µg as determined by the LAL method

Formulation

This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.

Storage and Handling

The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.

Country of Origin

USA

Shipping

Next Day Ambient

RRIDAB_2830827

Applications and Recommended Usage?
Quality Tested by Leinco

Western Blotting: To detect Mouse IGFBP-6 this monoclonal antibody can be used at a concentration of 1-2 µg/ml. This monoclonal antibody should be used in conjunction with compatible second-step reagents such as PN:R377 and a chromogenic substrate such as PN:T343. The detection limit for Mouse IGFBP-6 is 6 ng/lane under either reducing or non-reducing conditions. The sensitivity of detection may increase up to 50 fold when a chemiluminescent substrate is used.

Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity

Rat Anti-Mouse Insulin-Like Growth Factor Binding Protein 6 (IGFBP-6) (Clone 122316) recognizes an epitope on Mouse IGFBP-6. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background

Insulin-like growth factor binding protein 6, also known as IGFBP6 an extracellular protein with preferential affinity for insulin-like growth factor (IGF) II.¹ IGFBP6 plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase and may provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.

PubMed

IGFBP-6

NCBI Gene Bank ID

16012

UniProt.org

Information on Uniprot.org

References & Citations

1. Luthman, H. et al. (1999) Mamm Genome. 10: 376

View product citations for antibody PRODUCT_CODE on CiteAb

Certificate of Analysis

Request COA

Prod No.	Description
I-717	Anti-Human IGFBP-6 (Clone 164428)
I-706	Anti-Mouse IGFBP-6 (Clone 122316)
I-862	Anti-Human IGFBP-6
I-739	Anti-Mouse IGFBP-6
I-585	Recombinant Mouse IGFBP-6
I-849	Recombinant Human IGFBP-6

Formats Available

Prod No.	Description
I-706	Anti-Mouse IGFBP-6 (Clone 122316)

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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Anti-Mouse IGFBP-6 (Clone 122316)