Anti-Mouse NK1.1 – DyLight® 594
Anti-Mouse NK1.1 – DyLight® 594
Product No.: N222
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Clone PK136 Target NK1.1 Formats AvailableView All Product Type Monoclonal Antibody Alternate Names Natural Killer Cells, KR-P1C, NKR-P1B, Ly-55, CD161b, CD161c Isotype IgG2a Applications FC |
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Antibody DetailsProduct DetailsReactive Species Mouse Host Species Mouse Immunogen Purified Recombinant Mouse Natural Killer Cells (>98%) Product Concentration 0.2 mg/ml Formulation This DyLight® 594 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This DyLight® 594 conjugate is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day 2-8°C Excitation Laser Red Laser (590 nm) RRIDAB_2831451 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Clone PK136 recognizes mouse NK1.1. Background NK1.1 is a type II membrane protein that is part of the C-type lectin superfamily. NK1.1 contains a transmembrane domain and a cytoplasmic domain that are characteristic of C-type lectins. The function of NK cells is to mediate cytotoxicity and to secrete cytokines after immune stimulation. NK1.1 has been correlated with lysis of tumor cells In vitro and rejection of bone marrow allografts In vivo. It is also involved in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 is commonly used as a mouse NK cell marker. Antigen Distribution NK-1.1 is encoded by the NKR-P1B/NKR-P1C gene and expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. PubMed NCBI Gene Bank ID UniProt.org Research Area Immunology . Innate Immunity References & Citations1. Koo, G. C. and Peppard, J. R. (1986) Hybridoma 3:301 Technical Protocols Certificate of Analysis |
Formats Available
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Prod No. | Description |
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N228 | |
N106 | |
N109 | |
N108 | |
N107 | |
N110 | |
N220 | |
N221 | |
N222 | |
N224 | |
N226 | |
N123 | |
N268 |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
