Anti-Nitric Oxide Synthase, Neuronal Antibody (56116)
Anti-Nitric Oxide Synthase, Neuronal Antibody (56116)
Product No.: 56116
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Target Nitric Oxide Synthase, Neuronal Product Type Polyclonal Alternate Names EC 1.14.13.39, Constitutive NOS, NC-NOS, NOS type I, Neuronal NOS, N-NOS, nNOS, Peptidyl-cysteine S-nitrosylase NOS1, bNOS Isotype Rabbit Applications WB |
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Antibody DetailsProduct DetailsReactivity Species Human Host Species Rabbit Immunogen Peptide corresponding to aa 19-31 of human neuronal nitric oxide synthase. Product Concentration Lot Specific Formulation PBS, pH 7.4 with 0.02% sodium azide State of Matter Liquid Product Preparation Purified by immunoaffinity chromatography Storage and Handling This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco Immunoblotting: use at 1:500-1:1,000 dilution. In immunoblots, a band of approximately 155 kD is detected. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Rabbit Polyclonal Antibody specific to Neuronal NO Synthase Background Neuronal nitric oxide synthase
(nNOS) is one of three NOS
isoforms along with endothelial cell NOS
(eNOS) and inducible NOS (iNOS). The
three isoforms differ in primary
sequence, having only 50-60%
sequence identity. nNOS and iNOS can
be purified from cytosol while eNOS is
membrane-bound. All three NOS
isoforms catalyze the formation of NO
and L-citrulline from L-arginine. Antigen DetailsFunction Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. NCBI Gene Bank ID UniProt.org Research Area Neuroscience References & CitationsTechnical Protocols |
