Anti-Nitric Oxide Synthase, Neuronal Antibody (56116)

Anti-Nitric Oxide Synthase, Neuronal Antibody (56116)

Product No.: 56116

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Target
Nitric Oxide Synthase, Neuronal
Product Type
Polyclonal
Alternate Names
EC 1.14.13.39, Constitutive NOS, NC-NOS, NOS type I, Neuronal NOS, N-NOS, nNOS, Peptidyl-cysteine S-nitrosylase NOS1, bNOS
Isotype
Rabbit
Applications
WB

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Antibody Details

Product Details

Reactivity Species
Human
Host Species
Rabbit
Immunogen
Peptide corresponding to aa 19-31 of human neuronal nitric oxide synthase.
Product Concentration
Lot Specific
Formulation
PBS, pH 7.4 with 0.02% sodium azide
State of Matter
Liquid
Product Preparation
Purified by immunoaffinity chromatography
Storage and Handling
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
Country of Origin
USA
Shipping
Next Day 2-8°C
Applications and Recommended Usage?
Quality Tested by Leinco
Immunoblotting: use at 1:500-1:1,000 dilution. In immunoblots, a band of approximately 155 kD is detected.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Polyclonal Antibody specific to Neuronal NO Synthase
Background
Neuronal nitric oxide synthase (nNOS) is one of three NOS isoforms along with endothelial cell NOS (eNOS) and inducible NOS (iNOS). The three isoforms differ in primary sequence, having only 50-60% sequence identity. nNOS and iNOS can be purified from cytosol while eNOS is membrane-bound. All three NOS isoforms catalyze the formation of NO and L-citrulline from L-arginine.

Antigen Details

Function
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
NCBI Gene Bank ID
UniProt.org
Research Area
Neuroscience

References & Citations

General Western Blot Protocol
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.