Anti-PDRG Antibody (34012)
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Antibody DetailsProduct DetailsReactive Species Human Host Species Rabbit Immunogen Synthetic peptide corresponding to the aa sequence CDHLDKEIEKLRKQLK of human PDRG conjugated to KLH. Product Concentration Lot Specific Formulation PBS, pH 7.4. State of Matter Liquid Product Preparation Purified by peptide immuno-affinity chromatography Storage and Handling This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco Immunoblotting : use at 1:500-1:1,000 dilution.
Positive control: Normal human or mouse testis. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Rabbit Polyclonal Antibody specific to PDRG Background PDRG (p53 and DNA damage-regulated gene) is predominantly expressed in normal human testis but can be detected at lower levels in other organs. PDRG mRNA is upregulated after exposure of cells to UV radiation but is downregulated by tumor suppressor p53. Sequence analysis of PDRG promoter revealed the presence of an Oct-1 binding site as well as a p53 binding site. PDRG is a novel gene in that it is differentially regulated by p53 and UV radiation. Function May play a role in chaperone-mediated protein folding. {ECO:0000305}. NCBI Gene Bank ID UniProt.org Research Area Cancer Research References & CitationsLuo X et al. 2003 Oncogene 22: 7247-57. Technical Protocols  Certificate of Analysis |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
