Anti-Treponema pallidum, Tp47 (TPAL-6317)
Anti-Treponema pallidum, Tp47 (TPAL-6317)
Product No.: T816
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Clone TPAL-6317 Target Tp47 Formats AvailableView All Product Type Hybridoma Monoclonal Antibody Alternate Names Syphilis Isotype Mouse IgG2b Applications ELISA , IF , WB |
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Antibody DetailsProduct DetailsReactivity Species Treponema pallidum Host Species Mouse Product Concentration ≥1.0 mg/ml Purity ≥90% Formulation Formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration. State of Matter Liquid Product Preparation This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations. Storage and Handling This purified antibody is stable when stored at 2-8°C. Do not freeze. Regulatory Status Research Use Only Country of Origin USA Shipping 2-8°C Wet Ice Applications and Recommended Usage? Quality Tested by Leinco ELISA: 1:20-1:200, IF: 1:10-1:50, WB Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Anti-Treponema pallidum (Clone TPAL-6317) is specific for the immunodominant Tp47 protein of T. pallidum. This antibody does not cross react with Borrelia burgdorferi. Background Treponema pallidum is a Gram-negative spirochete that is the causative agent of the STI syphilis. Untreated syphilis typically has four stages, each marked with different symptoms. During late stages of infection, syphilis can lead to serious complications involving the nervous system, cardiovascular system, and other organs such as the eyes and ears. Syphilis can be passed from mother to child during both pregnancy and childbirth, leading to serious effects including miscarriages & stillbirths. Disease can also cause potential birth defects such as deformed bones, anemia, meningitis and deafness or blindness. Tp47 (p47) is a 47-kDa lipoprotein of T. pallidum that is strongly immunogenic. It has been shown to be an abundant penicillin-binding protein (PBP) in T. pallidum that is used in serological diagnostic screening. Antigen DetailsAntigen Tp47 Research Area Bacteria . Infectious Disease . Sexually Transmitted Infections . IVD Raw Material References & CitationsTechnical Protocols |
Formats Available
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