Anti-Trypsin Antibody (13403)
Anti-Trypsin Antibody (13403)
Product No.: 13403
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Clone TRYP11-224.3 Target Trypsin Formats AvailableView All Product Type Monoclonal Alternate Names EC 3.4.21.4, Anionic trypsin I, Anionic trypsin-I, β-trypsin, Cationic trypsinogen, Pretrypsinogen I, Trypsin I, Trypsin-1 [Cleaved into:α-trypsin chain 1;α-trypsin chain 2] Isotype Mouse IgG1 Applications ELISA |
Data
These antibodies recognize human pancreatic trypsin. They do not cross-react with human pancreatic chymotrypsin. - -
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Immunogen Purified human pancreatic trypsin. Product Concentration Lot Specific Formulation This monoclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.2 - 7.4 with no carrier protein or preservatives added. State of Matter Liquid Product Preparation Antibodies are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. Storage and Handling Upon initial thawing, appropriately aliquot and store at -80°C. For long-term storage, keep at -80°C. Avoid repeated freeze-thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco These antibodies have been qualified for use in ELISA to detect human pancreatic trypsin. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity These antibodies recognize human pancreatic trypsin. They do not cross-react with human pancreatic chymotrypsin. Background Trypsin is a serine protease found in the digestive system of many vertebrates where it hydrolyses proteins. Trypsin cleaves peptide chains mainly at the carboxyl side of the amino acids lysine or arginine, except when either is followed by proline. Trypsin is formed in the small intestine when its proenzyme form, the trypsinogen produced by the pancreas, is activated. Trypsin-1, also known as cationic trypsinogen, is the main isoform of trypsinogen secreted by the pancreas. Trypsin-2 is also known as anionic trypsinogen, and Trypsin-3 is also known as mesotrypsinogen. Function Has activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these substrates. {PubMed:7945238}. NCBI Gene Bank ID UniProt.org Research Area Enzymes References & CitationsTechnical Protocols Certificate of Analysis |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
