Anti-Viral CCI (Clone 112811)
Anti-Viral CCI (Clone 112811)
Product No.: C1449
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Clone 112811 Target CC Chemokine Inhibitor Formats AvailableView All Product Type Monoclonal Antibody Alternate Names P35 Isotype IgG1 Applications WB |
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Antibody DetailsProduct DetailsReactive Species Mouse Host Species Mouse Immunogen Sf 21-Derived Recombinant Viral CCI Endotoxin Level <0.1 EU/µg as determined by the LAL method Formulation This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. Storage and Handling The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months. Country of Origin USA Shipping Next Day Ambient RRIDAB_2828511 Applications and Recommended Usage? Quality Tested by Leinco Western Blotting: To detect Mouse CCI this monoclonal antibody can be used at a concentration of 1-2 µg/ml. This monoclonal antibody should be used in conjunction with compatible second-step reagents such as PN:M114 and a chromogenic substrate such as PN:T343. The detection limit for Mouse CCI is 2 ng/lane under either reducing or non-reducing conditions. The sensitivity of detection may increase up to 50 fold when a chemiluminescent substrate is used. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Mouse Anti-Mouse CC chemokine inhibitor (CCI) (Clone 112811) recognizes an epitope on Mouse CCI. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background Viral C-C chemokine inhibitor (vCCI) is a secreted, poxvirus-encoded C-C chemokine inhibitor1 that binds tightly and inhibit the action of many CC chemokines.2 VCCI can act as a potent anti-inflammatory therapeutic.3 PubMed References & Citations1. Don C et al. (1996) Proc Natl Acad Sci USA 96: 12379
2. LiWang PJ et al. (2006) Proc Natl Acad Sci USA 103: 13985
3. Patricia J Liwang et al. (2006) NIAID Technical Protocols Certificate of Analysis |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
