Anti-Mouse Vγ2 TCR – FITC
Anti-Mouse Vγ2 TCR – FITC
Product No.: T212
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Clone UC3-10A6 Target Vγ 2 T-Cell Receptor Formats AvailableView All Product Type Monoclonal Antibody Alternate Names Vγ2 T-cell receptor, T cell receptor gamma 2 Isotype IgG Applications FC |
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Antibody DetailsProduct DetailsReactive Species Mouse Host Species Armenian Hamster Immunogen G8 mouse T cells Product Concentration 0.2 mg/ml Formulation This Fluorescein (FITC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Product Preparation The antibody was purified by protein a affinity chromatography, and conjugated with FITC under optimal conditions. Storage and Handling This FITC monoclonal antibody conjugate is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day Ambient Excitation Laser Blue Laser (490 nm) RRIDAB_2892975 Applications and Recommended Usage? Quality Tested by Leinco Flow Cytometry: This antibody has been quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. Each lot of this antibody is quality control tested. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity This antibody reacts with Vγ 2 T-Cell Receptor (TCR)-bearing T lymphocytes. Background The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules. Antigen Distribution Vγ 2 T-Cell Receptor (TCR)-bearing T lymphocytes make up a significant proportion of γδ TCR-bearing cells in the late fetal and adult thymus and adult peripheral lymphoid tissues and lung. Function Might play a role in a previously unrecognized form of immunological surveillance for stress-induced self-antigens. Research Area Adaptive Immunity . Immunology References & CitationsHedrick, S. M. et al. (1990) Nature. 343:714 Technical Protocols Certificate of Analysis |
Formats Available
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Prod No. | Description |
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T554 | |
T212 | |
T219 | |
T353 | |
T211 | |
T213 | |
T594 | |
T704 | |
T210 |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
