Measles Virus Antigen (BA102VS)

Measles virus (Measles morbillivirus) is an enveloped, single-stranded, negative-sense RNA virus belonging to the genus Morbillivirus of the family Paramyxoviridae. The virus is highly contagious and spreads primarily through respiratory aerosol droplets. In unvaccinated populations, measles is usually acquired during childhood due to the high infectivity of the virus. Measles virus infection causes cold-like symptoms, fever, characteristic Koplik spots and maculopapular rash which spreads form the head to the trunk and lower extremities. Measles infection may be fatal even in children, which is often due to a measles-induced immunosuppression and subsequent opportunistic secondary infections. Despite vaccination since the 1960s, infections still appear worldwide, even in the U.S., where measles was declared eliminated in 2000.

Liquid

100 mM glycine buffer, pH 9.5.

Culture supernatant of measles virus infected cells is concentrated by ultrafiltration and ultracentrifugation. The resulting antigen preparation consists of a high concentration of virus and viral components and contains residual host cell material. The antigen is presented in 100 mM glycine buffer, pH 9.5.

Store at -65°C or lower. Avoid repeated freeze-thaw cycles. Sonicate before use. 10 years from date of manufacture (under recommended storage conditions).

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