Recombinant Human Eotaxin
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BackgroundThe CC-chemokine eotaxin is a potent eosinophil chemoattractant that stimulates recruitment of eosinophils from the blood to sites of allergic inflammation.1 Eotaxin and related molecules are potentially important endogenous signaling substances in allergic reactions.2 Eotaxin plays an important role not only by attracting eosinophils to the site of inflammation but also by damaging tissue by its capacity to induce the release of reactive oxygen species.3 Protein DetailsPurity ≥95% by SDS Page Endotoxin Level <1.0 EU/µg as determined by the LAL method Protein Accession No. P51671 Amino Acid Sequence GPASVPTTCC FNLANRKIPL QRLESYRRIT SGKCPQKAVI FKTKLAKDIC ADPKKKWVQD SMKYLDQKSP TPKP State of Matter Lyophilized Predicted Molecular Mass The predicted molecular weight of Recombinant Human Eotaxin is Mr 8.4 kDa. Predicted Molecular Mass 8.4 Formulation This protein was lyophilized from a sterile filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA). Storage and Stability This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. Country of Origin USA Shipping Next Day Ambient References & Citations1. Rankin SM. et al. (1998) Blood. 91:2240
2. Williams TJ. et al. (1993) Biochem Biophys Res Commun. 197:1167
3. Kapp A. et al. (1996) Eur J Immunol. 26:1919 Certificate of AnalysisIMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein. |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.