Recombinant Human Eotaxin

Recombinant Human Eotaxin

Product No.: E196

[product_table name="All Top" skus="E196"]

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Alternate Names
CCL11, MGC22554, SCYA11, Eosinophil Chemotactic Protein
Product Type
Recombinant Protein
Expression Host
E. coli Cells
Species
Human

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Background

The CC-chemokine eotaxin is a potent eosinophil chemoattractant that stimulates recruitment of eosinophils from the blood to sites of allergic inflammation.1
Eotaxin and related molecules are potentially important endogenous signaling substances in allergic reactions.2 Eotaxin plays an important role not only by attracting eosinophils to the site of inflammation but also by damaging tissue by its capacity to induce the release of reactive oxygen species.3

Protein Details

Purity
≥95% by SDS Page
Endotoxin Level
<1.0 EU/µg as determined by the LAL method
Protein Accession No.
P51671
Amino Acid Sequence
GPASVPTTCC FNLANRKIPL QRLESYRRIT SGKCPQKAVI FKTKLAKDIC ADPKKKWVQD SMKYLDQKSP TPKP
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human Eotaxin is Mr 8.4 kDa.
Predicted Molecular Mass
8.4
Formulation
This protein was lyophilized from a sterile filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA).
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient

References & Citations

1. Rankin SM. et al. (1998) Blood. 91:2240 2. Williams TJ. et al. (1993) Biochem Biophys Res Commun. 197:1167 3. Kapp A. et al. (1996) Eur J Immunol. 26:1919

Certificate of Analysis

IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.