Recombinant Human FGF R1β (IIIc)

Fibroblast growth factor receptor-1 beta (FGFR1- beta) is an isoform of FGFR1 which is a receptor tyrosine kinase. FGFR1-beta is expressed in basal epithelial cells and smooth muscle cells.¹ FGF R1β supports progression and chemoresistance in subsets of acute myeloid leukemias (AML).²

Fc Fusion Protein

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Arg22

Lyophilized

The predicted molecular weight of Recombinant Human FGF R1β (IIIc) is Mr 56 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 90-95 kDa.

56

This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Next Day Ambient

1. Moscatelli, D. et al. (2007) Prostate 67: 115
2. Raffi, S. et al. (2006) Leukemia 20: 979