Recombinant Human gAcrp30

gAdiponectin (gAcrp30) is an adipocyte complement-related protein and is a member of the family of defense collagens (1). gAdiponectin is produced and secreted exclusively by adipocytes, and is a relatively abundant plasma protein, accounting for up to 0.05% of total serum protein. The signaling receptors for adiponectin and gAcrp30 have recently been identified and named AdipoR1 and AdipoR2 (2). AdipoR1 is produced primarily in muscle while AdipoR2 is predominantly expressed in the liver. gAcrp30 is an anti-diabetic and anti-antherogenic hormone that plays important roles in the regulation of lipid and glucose metabolism (3).

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Solution

The predicted molecular weight of Recombinant Human gAcrp30 is Mr 16.7 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 20 kDa.

16.7

This recombinant protein solution was 0.2 µm filtered and formulated in modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives present.

This protein can be stored under sterile conditions at 2° to 8°C for four months without detectable change of its oligomeric state.

Next Day 2-8°C

1. Scherer, P. E. et al. (1995) J. Biol. Chem. 270:26746 2. Yamauchi, T. et al. (2003) Nature 423:762 3. Hu, E. et al. (1996) J. Biol. Chem. 271:10697