Recombinant Human ICAM-2
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BackgroundIntercellular adhesion molecule 2 (ICAM2), also known as CD102 (Cluster of Differentiation 102), is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins that bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Protein DetailsPurity >95% by SDS-PAGE and analyzed by silver stain. Endotoxin Level <0.1 EU/µg as determined by the LAL method Fusion Protein Tag Fc Fusion Protein Protein Accession No. Amino Acid Sequence dekvfevh vrpkklavep kgslevncst tcnqpevggl etslnkilld eqaqwkhylv snishdtvlq chftcsgkqe smnsnvsvyq pprqviltlq ptlvavgksf tiecrvptve pldsltlflf rgnetlhyet fgkaapapqe atatfnstad redghrnfsc lavldlmsrg gni (IEGRMD) (Human IgG1) hhhhhh N-terminal Sequence Analysis Lys25 State of Matter Lyophilized Predicted Molecular Mass The predicted molecular weight of Recombinant Human ICAM-2 is Mr 50 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 86 kDa. Predicted Molecular Mass 50 Formulation This recombinant protein was lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4 containing calcium and magnesium with 1% sorbitol. Storage and Stability This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. Country of Origin USA Shipping Next Day Ambient NCBI Gene Bank Certificate of AnalysisIMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein. |
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