Recombinant Human Myostatin Propeptide
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BackgroundMyostatin propeptide (MRPO) has a very high binding affinity to myostatin and is a natural inhibitor of myostatin. MPRO is considered an attractive strategy for the treatment of muscle-wasting diseases such as muscular dystrophies.1 Disruption of myostatin function by its propeptide, shifts dietary fat utilization toward muscle tissues with minimal effects on adiposity, therefore, enhancing muscle growth by myostatin propeptide during the early developmental stage. It may also serve as an effective means for obesity prevention.2 Protein DetailsPurity >98% by SDS Page Endotoxin Level <1.0 EU/µg Biological Activity Data not yet available. Protein Accession No. O14793(24-266) Storage and Stability The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA References & Citations1. Xiao X. et al. (2008) Hum Gene Ther. 19: 241
2. Baoping Z. et al. (2006) Molec. Reprod. Development 73: 462
Certificate of AnalysisIMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein. |
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