Recombinant Human RELMβ
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BackgroundResistin-Like Molecule Beta (RELMβ) is a novel class of cysteine-rich proteins secreted into the circulation implicated in hepatic insulin resistance and inflammation. RELMβ is specifically produced by intestinal goblet cells1 and can be found in high quantities in stool. RELMβ may be involved in the development of scleroderma-associated pulmonary hypertension.2 Protein DetailsPurity >97% by SDS-PAGE and HPLC Endotoxin Level <0.1 EU/µg as determined by the LAL method Biological Activity Data not yet available. Protein Accession No. Amino Acid Sequence MQCSLDSVMD KKIKDVLNSL EYSPSPISKK LSCASVKSQG RPSSCPAGMA VTGCACGYGC GSWDVQLETT CHCQCSVVDW TTARCCHLT State of Matter Lyophilized Predicted Molecular Mass The molecular weight of Recombinant Human RELMβ is Mr 19 kDa. Formulation This RELM beta protein was Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA) Storage and Stability The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient References & Citations1. Marie JC et al. (2008) Inflamm Bowel Dis. 14: 931
2. Johns RA et al. (2009) Am J Respir Cell Mol Biol. 87: 820
Certificate of AnalysisIMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein. |
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