Recombinant Human TGF-β2 (Mammalian Derived)
Recombinant Human TGF-β2 (Mammalian Derived)
Product No.: T226
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Alternate Names Transforming Growth Factor Beta 2 [Mammalian Derived], Glioblastoma-Derived T-Cell Suppressor Factor, G-TSF, BSC-1 Cell Growth Inhibitor, Polyergin, Cetermin Product Type Recombinant Protein Expression Host NS0 Cells Species Human |
Data
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BackgroundTransforming growth factor-beta 2 (TGF-β2) is a secreted protein known as a potent cytokine that modulates embryonic development, bone formation, mammary development, wound healing, hematopoiesis, cell cycle progression and the production of the extracellular matrix. Protein DetailsPurity >97% by SDS-PAGE and analyzed by silver stain. Endotoxin Level <0.1 EU/µg as determined by the LAL method Biological Activity The biological activity of Human Transforming Growth Factor Beta 2 is determined by its ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The ED<sub>50</sub> was found to be 5 x 10<sup>6</sup> units/mg. Protein Accession No. Amino Acid Sequence Ala303-Ser414 N-terminal Sequence Analysis Ala303 State of Matter Lyophilized Predicted Molecular Mass The predicted molecular weight of Recombinant Human TGF-β2 is Mr 12.7 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is 12 kDa (reducing conditions) and
24 kDa (non-reducing conditions). Predicted Molecular Mass 12.7 Formulation This recombinant protein was lyophilized from a 0.2 μm filtered solution in 35% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA). Storage and Stability This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. Country of Origin USA Shipping Next Day Ambient Certificate of AnalysisIMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein. |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
