Recombinant Human TRAIL R3

TNF-related apoptosis-inducing ligand receptor 3 (TRAIL R3) is an antagonist decoy receptor¹ that can inhibit TRAIL-induced apoptosis.² TRAIL R3 is a plasma membrane-bound protein capable of high affinity interaction with the TRAIL ligand.³

Fc Fusion Protein

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Ala26

Lyophilized

The predicted molecular weight of Recombinant Human TRAIL R3 is Mr 48 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 75-90 kDa.

48

This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Next Day Ambient

1. Fornace Jr., AJ. et al. (1999) Oncogene 18: 4153
2. Büchler, MW. et al. (2001) Anticancer Res. 21: 3153 3. Smith, CA. et al. (1997) J Exp Med. 186: 1165