Recombinant Mouse Axl

Axl is a member of receptor tyrosine kinases characterized by an extracellular domains (ECD) resembling cell adhesion molecules and unique sequences in the kinase domain. In addition, Axl is transforming in both fibroblast and hematopoietic cells, and appears to be involved in mesenchymal development.¹ Axl regulates cell migration, phagocytosis and apoptosis.²

Fc Fusion Protein

h kdtqteagsp fvgnpgnitg argltgtlrc elqvqgeppe vvwlrdgqil eladntqtqv plgedwqdew kvvsqlrisa lqlsdageyq cmvhlegrtf vsqpgfvgle glpyfleepe dkavpantpf nlscqaqgpp epvtllwlqd avplapvtgh ssqhslqtpg lnktssfsce ahnakgvtts rtatitvlpq rphhlhvvsr qptelevawt pglsgiyplt hcnlqavlsd dgvgiwlgks dppedpltlq vsvpphqlrl ekllphtpyh iriscsssqg pspwthwlpv ettegvplgp penvsamrng sqvlvrwqep rvplqgtllg yrlayrgqdt pevlmdiglt revtlelrgd rpvanltvsv taytsagdgp wslpvplepw rpgqgqplhh lvsepppraf swpiegrmdp kscdkthtcp pcpapellgg psvflfppkp kdtlmisrtp evtcvvvdvs hedpevkfnw yvdgvevhna ktkpreeqyn styrvvsvlt vlhqdwlngk eykckvsnka lpapiektis kakgqprepq vytlppsrde ltknqvsltc lvkgfypsdi avewesngqp ennykttppv ldsdgsffly skltvdksrw qqgnvfscsv mhealhnhyt qkslslspgk hhhhhh

His20

Lyophilized

The predicted molecular weight of Recombinant Mouse Axl is Mr 73.8 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 100-110 kDa.

73.8

This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Next Day Ambient

1. Liu, ET. et al. (1995) J Mol Biol. 270: 551
2. Berk, BC. et al. (2006) Circ Res. 98: 1446