Recombinant Mouse Granzyme B
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BackgroundGranzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1), also known as GZMB, is a serine protease involved in many pathologies, including viral infections, autoimmunity, transplant rejection, and antitumor immunity.1 Granzyme B may be a useful prognostic marker in early rheumatoid arthritis and may provide important clues to the pathogenesis of this disease.2 Protein DetailsPurity >98% by SDS Page and HPLC Endotoxin Level <0.1 EU/µg as determined by the LAL method State of Matter Lyophilized Predicted Molecular Mass The molecular weight of Recombinant Mouse Granzyme B is Mr 34-37 kDa. Storage and Stability This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. Country of Origin USA Shipping Next Day Ambient References & Citations1. Ioannis Theodorou et al. (2003) PNAS 100: 2562
2. PP Tak et al. (2005) Annals of Rheumatic Diseases 64: 715
Certificate of AnalysisIMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein. |
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