Recombinant Mouse IL-21R

The biological activity of Mouse IL-21 R was determined by its ability to inhibit IL21 dependent proliferation of N1186 human T-cells. The expected ED₅₀ is typically 0.75 - 3 μg/ml in the presence of 100 ng/ml of rmIL21.

Fc Fusion Protein

c ldltcytdyl wtitcvletr spnpsilslt wqdeyeelqd qetfcslhrs ghntthiwyt chmrlsqfls devfivnvtd qsgnnsqecg sfvlaesikp applnvtvaf sgrydiswds aydepsnyvl rgklqyelqy rnlrdpyavr pvtklisvds rnvsllpeef hkdssyqlqv raapqpgtsf rgtwsewsdp vifqtqagep eagwdpiegr mdpkscdkth tcppcpapel lggpsvflfp pkpkdtlmis rtpevtcvvv dvshedpevk fnwyvdgvev hnaktkpree qynstyrvvs vltvlhqdwl ngkeykckvs nkalpapiek tiskakgqpr epqvytlpps rdeltknqvs ltclvkgfyp sdiavewesn gqpennyktt ppvldsdgsf flyskltvdk srwqqgnvfs csvmhealhn hytqkslsls pgk

Cys20

Lyophilized

The predicted molecular weight of Recombinant Mouse IL-21R is Mr 51.5 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 70-80 kDa.

51.5

This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Next Day Ambient

1. King, IL. et al. (2010) J. Immunol. 185:6138.
2. Tortola, L. et al. (2010) Blood. 116:5200.