Recombinant Mouse OSM Rβ

Oncostatin M (OSM) is a cytokine produced by activated T lymphocytes and macrophages. The biological activities of OSM are mediated through two types of receptor complexes, the LIF/OSM shared receptor (type I) and OSM-specific receptor (OSM-R, type II).¹ OSM is important in liver development, haematopoeisis, inflammation and possibly CNS development.

Fc Fusion Protein

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Glu24

Lyophilized

The predicted molecular weight of Recombinant Mouse OSM Rβ is Mr 109 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 120-150 kDa.

109

This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Next Day Ambient

1. Vestal, RE. et al. (1998) Cytokine 10: 295