Recombinant Rat IL-17
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BackgroundInterleukin 17 (IL-17) is a T cell cytokine that induces monocyte migration and inflammation.1 IL-17-producing cell could serve as a potential prognostic marker and a novel therapeutic target for hepatocellular carcinoma (HCC).2 IL-17 may be important in recruiting monocytes into the joints of patients with RA, supporting IL-17 as a therapeutic target in RA.1 Protein DetailsPurity <95% by SDS Page Biological Activity Recombinant Rat IL-17A is fully biologically active when compared to standards via dose-dependent induction of IL-6 production in cultured rat fibroblasts. Protein Accession No. Amino Acid Sequence MAVLIPQSSV CPNAEANNFL QNVKVNLKVL NSLSSKASSR RPSDYLNRST SPWTLSRNED PDRYPSVIWE AQCRHQRCVN AEGKLDHHMN SVLIQQEILV LKREPEKCPF TFRVEKMLVG VGCTCVSSIV RHAS State of Matter Lyophilized Predicted Molecular Mass The predicted molecular weight of Recombinant Rat IL-17A is Mr 30.0 kDa. Predicted Molecular Mass 30.0 Formulation The protein was 0.2 µm filtered and lyopohilized from 10 mM NaCitrate, pH 3.0 Storage and Stability The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient NCBI Gene Bank References & Citations1. Pope, RM. et al. (2009) J Immunol. 182: 3884 2. Zheng, L. et al. (2009) J Hepatol. 50(5):980-989. Certificate of AnalysisIMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein. |
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