Recombinant Viral CCI

Viral C-C chemokine inhibitor (vCCI) is a secreted, poxvirus-encoded C-C chemokine inhibitor¹ that binds tightly and inhibit the action of many CC chemokines.² VCCI can act as a potent anti-inflammatory therapeutic.²

Fc Fusion Protein

mpas lqqsssssss cteeenkhhm gidviikvtk qdqtptndki cqsvteites esdpdpeves eddstsvedv dppttyysii ggglrmnfgf tkcpqiksis esadgntvna rlssvspgqg kdspaitree alamikdcev sidircseee kdsdikthpv lgsnishkkv syediigsti vdtkcvknle fsvrigdmck esselevkdg fkyvdgsase gatddtslid stklkacv (Viral CCI Pro18-Val258) ie grmdpkscdk thtcppcpap ellggpsvfl fppkpkdtlm isrtpevtcv vvdvshedpe vkfnwyvdgv evhnaktkpr eeqynstyrv vsvltvlhqd wlngkeykck vsnkalpapi ektiskakgq prepqvytlp psrdeltknq vsltclvkgf ypsdiavewe sngqpennyk ttppvldsdg sfflyskltv dksrwqqgnv fscsvmheal hnhytqksls lspgkhhhhh h

Met17 & Pro18

Lyophilized

The predicted molecular weight of Recombinant Viral CCI is Mr 57 kDa.

57

This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Next Day Ambient

1. Don, C. et al. (1996) Proc Natl Acad Sci USA 96: 12379
2. LiWang, PJ et al. (2006) Proc Natl Acad Sci USA 103: 13985