TACI Blocking Peptide
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Antibody DetailsProduct DetailsReactive Species Human Product Concentration 0.2 mg/ml Amino Acid Location This peptide sequence is located at amino acids 2 to 16 of Human TACI protein. Formulation This peptide is formulated in PBS pH 7.2 (0.01 M Sodium Phosphate, 0.13 M NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. Storage and Handling Store this peptide in working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionBackground Transmembrane activator & calcium modulator and cyclophilin ligand (CAML) interactor (TACI) is lymphocyte specific member1,2 of the tumor necrosis factor-receptor superfamily3 and is expressed in B-lymphocytes and may act to regulate humoral immunity.4 TACI also serves as a receptor for B-cell activating factor of the TNF family (BAFF) and as a proliferation-inducing ligand (APRIL).5 References & Citations1. Schwaller J et al. (2007) Blood 109: 331
2. Slazer U et al. (2005) Nat Genet. 37: 820
3. Bonilla FA et al. (2006) Curr Allergy Asthma Rep. 6: 357
4. Bram RJ et al. (2000) Mamm Genome. 11: 628
5. Kobata T et al. (2007) Blood 109: 2961 |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
